Rational Metabolic Engineering & Strain Design

Cellular Network Analysis & Modelling

Bioprocess Optimisation

Metabolic Engineering Workshop by qBiome Research at IISc

qBiome Team at the Global-Bio start-up conclave at Delhi

qBiome Research

Underlying every living cell are billions of molecules interacting in a beautifully concerted network of metabolic, regulatory and signalling pathways. How do we re-engineer such complex cellular machinery towards a particular metabolic goal?
At Qbiome, we offer customised cellular, metabolic and process engineering solutions for biotech, pharma and chemical industry. Our services include (a) end-to-end solutions for the entire process, (b) quantitative optimisation of individual steps in existing processes and (c) solutions for process modification.

Our Services

We offer customised cellular, metabolic and process engineering solutions for biotech, pharma and chemical industry. Our services include (a) end-to-end solutions for the entire process, (b) quantitative optimisation of individual steps in existing processes and (c) solutions for process modification. Our key strengths are quantitative modelling of your bioprocess, by integrating a high level of domain knowledge and cutting-edge modelling skills with the best engineering optimisation methodologies.

Metabolic and Cellular Engineering

Genome-scale Modelling; Metabolic Modelling; Modelling of Cellular Regulation; Retrosynthesis Predictions For Synthesis of Novel Compounds, Cellular Optimisation.

Computational Drug Design and Protein Engineering

Lead and target identification; Identification of optimal targeting strategy; Pharmacodynamics, Pharmacodynamics; Host-Pathogen interaction studies.

Bioreactor Design and Reactor Optimization

Reaction design; Optimisation; Fed-batch and continuous Processing; Scale-up; Data reconciliation and analysis, Machine learning; Process control, Fault Diagnosis.

Our Process

We provide and end-to end process modelling solution beginning with strain modelling, through integrated genome-scale models of metabolism and signalling, all the way up to reactor design, operation and control.

1

Genome-scale Modelling

2

Strain Optimisation

3

Reactor Design

4

Process Optimisation

5

Scale-up

6

Reactor Control and Management

The Team

We have a highly skilled team guided by active researchers with proven track records in the forefront of quantitative biology

Venkatesh K V

Co-Founder

25+ years of experience in process modelling and systems biology

Nagasuma Chandra

Co-Founder

25+ years of experience in bioinformatics, protein engineering and systems biology

Karthik Raman

Co-Founder

10 years of experience in systems biology, metabolic pathway modelling

Rajiv K

Research Scientist

B.Tech and M.Tech in Biological Engineering, IIT Madras

Sunanda

Research Scientist

B.Tech and M.Tech in Bioinformatics, Sastra University

Projects

We have executed multiple academic and industrial research projects in the areas of genome-scale modelling, metabolic engineering, strain optimisation, bioreactor design and control

Hyaluronic acid

in Lactoccus lactis

alpha-tocopherol

in Helianthus annuus




Careers

We are looking for dynamic motivated individuals to join our team and build solutions in the areas of metabolic engineering and process optimisation.

Research Scientist

Job Description

  • Build and simulate models of microbial metabolic networks
  • Survey literature
  • Develop tools and customised pipelines for effective project execution
  • Effectively communicate with client research team
  • Document models and results and communicate with team members and client

Requirements

  • ME/MTech/MS/PhD
  • BE/BTech in Chemical Engineering / Biotechnology / other areas
  • Experience with mathematical modelling
  • Ability to program in a high-level programming langugage such as MATLAB/Python
  • Excellent communication skills and leadership qualities
  • Familiarity with ODE-based modelling / constraint-based modelling will be helpful
  • Knowledge of optimisation / process modelling will be a plus
  • Projects / publications in relevant areas will be a huge plus

Software Developer

Job Description

  • Develop tools and customised pipelines per client needs
  • Develop tools for internal use
  • Develop documentation and deploy software

Requirements

  • BE/BTech in Computer Science or other disciplines
  • Ability to program in a high-level programming langugage such as MATLAB/Python
  • Knowledge of Web Development, Version control systems such as Git
  • Excellent communication skills

Contact Us

Our registered office is in Chennai.
Email us at rajiv.k@qbiome.com
You can call us at +91 9360567514

qBiome Research Private Limited

41C Beach Road, Kalakshetra Colony
Besant Nagar, Chennai - 600 090